Drotaverine Hydrochloride 80 mg + Mefenarnic Acid 250 mg

The combination of SPASTILL-M (Drotaverine Hydrochloride 80 mg + Mefenamic Acid 250 mg) is commonly used to provide relief from spasmodic pain and inflammation.

Uses and mechanisms of SPASTILL-M

Drotaverine Hydrochloride 80 MG

Class: Antispasmodic 

Uses: Drotaverine is used to treat biliary, urinary, and gastrointestinal smooth muscle spasms. For ailments like renal colic, irritable bowel syndrome, and dysmenorrhea (painful menstruation), it is frequently recommended.

Mechanism of Action: It functions by blocking phosphodiesterase IV, which raises the levels of cyclic AMP (cAMP). This results in smooth muscular relaxation, which lessens discomfort and spasms.

Mefenamic Acid 250 mg

Class: NSAIDs (non-steroidal anti-inflammatory drugs)

Uses: Mefenamic acid is used to treat inflammation and mild to moderate pain, especially menstrual pain. It works well for rheumatoid arthritis, osteoarthritis, and other musculoskeletal diseases.

Mechanism of Action: It reduces the production of prostaglandins, which are implicated in pain and inflammation processes, by blocking the cyclooxygenase (COX) enzymes.